Structure and function of the human Werner syndrome gene promoter: evidence for transcriptional modulation.

The Werner syndrome (WS) is an autosomal recessive segmental progeroid syndrome caused by mutations in a novel member ( WRN ) of the RecQ family of helicases. Somatic WS cells are hypermutable and have elongated S phases, suggesting possible defects in DNA replication and/or repair. As an initial ap...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Wang, L, Hunt, K E, Martin, G M, Oshima, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1998
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.15.3480
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