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Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation.

Rad51 proteins share both structural and functional homologies with the bacterial recombinase RecA. The human Rad51 (HsRad51) is able to catalyse strand exchange between homologous DNA molecules in vitro . However the biological functions of Rad51 in mammals are largely unknown. In order to address...

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Udgivet i:Nucleic Acids Res
Principais autores: Vispé, S, Cazaux, C, Lesca, C, Defais, M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147643/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9611228/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.12.2859
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