Different Roles for Nonhomologous End Joining and Homologous Recombination following Replication Arrest in Mammalian Cells

Homologous recombination (HR) and nonhomologous end joining (NHEJ) play overlapping roles in repair of DNA double-strand breaks (DSBs) generated during the S phase of the cell cycle. Here, we characterized the involvement of HR and NHEJ in the rescue of DNA replication forks arrested or slowed by tr...

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Detalhes bibliográficos
Main Authors: Lundin, Cecilia, Erixon, Klaus, Arnaudeau, Catherine, Schultz, Niklas, Jenssen, Dag, Meuth, Mark, Helleday, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133974/
https://ncbi.nlm.nih.gov/pubmed/12138197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.16.5869-5878.2002
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