Different Roles for Nonhomologous End Joining and Homologous Recombination following Replication Arrest in Mammalian Cells

Homologous recombination (HR) and nonhomologous end joining (NHEJ) play overlapping roles in repair of DNA double-strand breaks (DSBs) generated during the S phase of the cell cycle. Here, we characterized the involvement of HR and NHEJ in the rescue of DNA replication forks arrested or slowed by tr...

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Détails bibliographiques
Auteurs principaux: Lundin, Cecilia, Erixon, Klaus, Arnaudeau, Catherine, Schultz, Niklas, Jenssen, Dag, Meuth, Mark, Helleday, Thomas
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Cell Growth and Development
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC133974/
https://ncbi.nlm.nih.gov/pubmed/12138197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.16.5869-5878.2002
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