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Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation.

Rad51 proteins share both structural and functional homologies with the bacterial recombinase RecA. The human Rad51 (HsRad51) is able to catalyse strand exchange between homologous DNA molecules in vitro . However the biological functions of Rad51 in mammals are largely unknown. In order to address...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Vispé, S, Cazaux, C, Lesca, C, Defais, M
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1998
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147643/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9611228/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.12.2859
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