Visualisation of extensive water ribbons and networks in a DNA minor-groove drug complex.
The crystal structure is reported of a complex between an ethyl derivative of the minor-groove drug furamidine and the dodecanucleotide duplex d(CGCGAATTCGCG)2, which has been refined to 1.85 A resolution and an R factor of 16.6% for data collected at -173 degreesC. An exceptionally large number (22...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9611230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.12.2873 |
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