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Visualisation of extensive water ribbons and networks in a DNA minor-groove drug complex.
The crystal structure is reported of a complex between an ethyl derivative of the minor-groove drug furamidine and the dodecanucleotide duplex d(CGCGAATTCGCG)2, which has been refined to 1.85 A resolution and an R factor of 16.6% for data collected at -173 degreesC. An exceptionally large number (22...
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主要な著者: | , , |
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フォーマット: | Artigo |
言語: | Inglês |
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1998
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC147633/ https://ncbi.nlm.nih.gov/pubmed/9611230 |
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