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Visualisation of extensive water ribbons and networks in a DNA minor-groove drug complex.

The crystal structure is reported of a complex between an ethyl derivative of the minor-groove drug furamidine and the dodecanucleotide duplex d(CGCGAATTCGCG)2, which has been refined to 1.85 A resolution and an R factor of 16.6% for data collected at -173 degreesC. An exceptionally large number (22...

詳細記述

保存先:
書誌詳細
主要な著者: Guerri, A, Simpson, I J, Neidle, S
フォーマット: Artigo
言語:Inglês
出版事項: 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC147633/
https://ncbi.nlm.nih.gov/pubmed/9611230
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