Visualisation of extensive water ribbons and networks in a DNA minor-groove drug complex.

The crystal structure is reported of a complex between an ethyl derivative of the minor-groove drug furamidine and the dodecanucleotide duplex d(CGCGAATTCGCG)2, which has been refined to 1.85 A resolution and an R factor of 16.6% for data collected at -173 degreesC. An exceptionally large number (22...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Guerri, A, Simpson, I J, Neidle, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1998
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9611230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.12.2873
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