Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes

Using genetic and pharmacological approaches, we demonstrate that both RARγ/RXRα heterodimers involved in repression events, as well as PPARβ(δ)/RXRα heterodimers involved in activation events, are cell-autonomously required in suprabasal keratinocytes for the generation of lamellar granules (LG), t...

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Bibliografiska uppgifter
Huvudupphovsmän: Calléja, Cécile, Messaddeq, Nadia, Chapellier, Benoit, Yang, Haiyuan, Krezel, Wojciech, Li, Mei, Metzger, Daniel, Mascrez, Bénédicte, Ohta, Kiminori, Kagechika, Hiroyuki, Endo, Yasuyuki, Mark, Manuel, Ghyselinck, Norbert B., Chambon, Pierre
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2006
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1475764/
https://ncbi.nlm.nih.gov/pubmed/16751185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.368706
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