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Ligand-dependent contribution of RXRβ to cholesterol homeostasis in Sertoli cells

We show that mice expressing retinoid X receptor β (RXRβ) impaired in its transcriptional activation function AF-2 (Rxrb(af20) mutation) do not display the spermatid release defects observed in RXRβ-null mutants, indicating that the role of RXRβ in spermatid release is ligand-independent. In contras...

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Main Authors: Mascrez, Bénédicte, Ghyselinck, Norbert B, Watanabe, Mitsuhiro, Annicotte, Jean-Sébastien, Chambon, Pierre, Auwerx, Johan, Mark, Manuel
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299005/
https://ncbi.nlm.nih.gov/pubmed/14993927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400094
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