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A transcriptionally silent RXRα supports early embryonic morphogenesis and heart development
Retinoic acid (RA) receptors (RARs) α, β, and γ heterodimerized with rexinoid receptors (RXRs) α, β, and γ mediate the RA signal. To analyze the contribution of the transcriptional activity of RXRα, the main RXR during embryogenesis, we have engineered a mouse line harboring a transcriptionally sile...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657455/ https://ncbi.nlm.nih.gov/pubmed/19255444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813143106 |
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