CSA-dependent degradation of CSB by the ubiquitin–proteasome pathway establishes a link between complementation factors of the Cockayne syndrome

Mutations in the CSA or CSB complementation genes cause the Cockayne syndrome, a severe genetic disorder that results in patients’ death in early adulthood. CSA and CSB act in a transcription-coupled repair (TCR) pathway, but their functional relationship is not understood. We have previously shown...

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Autori principali: Groisman, Regina, Kuraoka, Isao, Chevallier, Odile, Gaye, Nogaye, Magnaldo, Thierry, Tanaka, Kiyoji, Kisselev, Alexei F., Harel-Bellan, Annick, Nakatani, Yoshihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2006
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1475755/
https://ncbi.nlm.nih.gov/pubmed/16751180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.378206
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