Meiotic double-strand breaks in yeast artificial chromosomes containing human DNA.
Meiotic recombination in the yeast Saccharomyces cerevisiae is initiated by double-strand breaks (DSB) in chromosomal DNA. These DSB, which can be mapped in the rad 50S mutant yeast strain, are caused by a topoisomerase II-like enzyme, the protein Spo11. Evidence suggests that this protein is locate...
Guardat en:
| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9580694/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.10.2415 |
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