Meiotic double-strand breaks in yeast artificial chromosomes containing human DNA.

Meiotic recombination in the yeast Saccharomyces cerevisiae is initiated by double-strand breaks (DSB) in chromosomal DNA. These DSB, which can be mapped in the rad 50S mutant yeast strain, are caused by a topoisomerase II-like enzyme, the protein Spo11. Evidence suggests that this protein is locate...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Ira, G, Svetlova, E, Filipski, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9580694/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.10.2415
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