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Triple helices formed at oligopyrimidine*oligopurine sequences with base pair inversions: effect of a triplex-specific ligand on stability and selectivity.

Oligonucleotide-directed triple helix formation is mostly restricted to oligopyrimidine*oligopurine sequences of double helical DNA. An interruption of one or two pyrimidines in the oligopurine target strand leads to a strong triplex destabilisation. We have investigated the effect of nucleotide ana...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Kukreti, S, Sun, J S, Loakes, D, Brown, D M, Nguyen, C H, Bisagni, E, Garestier, T, Helene, C
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147530/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9547278/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.9.2179
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