Triple helices formed at oligopyrimidine*oligopurine sequences with base pair inversions: effect of a triplex-specific ligand on stability and selectivity.

Oligonucleotide-directed triple helix formation is mostly restricted to oligopyrimidine*oligopurine sequences of double helical DNA. An interruption of one or two pyrimidines in the oligopurine target strand leads to a strong triplex destabilisation. We have investigated the effect of nucleotide ana...

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Bibliographic Details
Main Authors: Kukreti, S, Sun, J S, Loakes, D, Brown, D M, Nguyen, C H, Bisagni, E, Garestier, T, Helene, C
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC147530/
https://ncbi.nlm.nih.gov/pubmed/9547278
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