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The Kinesin KIF1C and Microtubule Plus Ends Regulate Podosome Dynamics in Macrophages

Microtubules are important for the turnover of podosomes, dynamic, actin-rich adhesions implicated in migration and invasion of monocytic cells. The molecular basis for this functional dependency, however, remained unclear. Here, we show that contact by microtubule plus ends critically influences th...

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Autors principals: Kopp, Petra, Lammers, Reiner, Aepfelbacher, Martin, Woehlke, Günther, Rudel, Thomas, Machuy, Nikolaus, Steffen, Walter, Linder, Stefan
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474789/
https://ncbi.nlm.nih.gov/pubmed/16554367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-11-1010
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