Selective Toxicity of NSC 73306 in MDR1-positive cells as a New Strategy to Circumvent Multidrug Resistance in Cancer

ATP-binding cassette (ABC) proteins include the best known mediators of resistance to anticancer drugs. In particular, ABCB1 (MDR1/P-gp) extrudes many types of drugs from cancer cells, thereby conferring resistance to those agents. Attempts to overcome P-gp-mediated drug resistance using specific in...

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Détails bibliographiques
Auteurs principaux: Ludwig, Joseph A., Szakács, Gergely, Martin, Scott E., Chu, Benjamin F., Cardarelli, Carol, Sauna, Zuben E., Caplen, Natasha J., Fales, Henry M., Ambudkar, Suresh V., Weinstein, John N., Gottesman, Michael M.
Format: Artigo
Langue:Inglês
Publié: 2006
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474781/
https://ncbi.nlm.nih.gov/pubmed/16651436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-3322
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