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β-Scorpion toxin effects suggest electrostatic interactions in domain II of voltage-dependent sodium channels

β-Scorpion toxins specifically modulate the voltage dependence of sodium channel activation by acting through a voltage-sensor trapping model. We used mutagenesis, functional analysis and the action of β-toxin as tools to investigate the existence and role in channel activation of molecular interact...

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Bibliografische gegevens
Hoofdauteurs: Mantegazza, Massimo, Cestèle, Sandrine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474769/
https://ncbi.nlm.nih.gov/pubmed/16020455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.093484
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