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Role of aspartate 298 in mouse 5-HT(3A) receptor gating and modulation by extracellular Ca(2+)
The TM2–TM3 extracellular loop is critical for activation of the Cys-loop family of ligand-gated ion channels. The contribution of aspartate 298 (D298), an amino acid that links the transmembrane domain 2 (TM2) to the TM2–TM3 loop, in mouse 5-hydroxytryptamine(3A) (5-HT(3A)) receptor function was pr...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1474733/ https://ncbi.nlm.nih.gov/pubmed/16096341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.092866 |
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