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Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells.

It is widely accepted that most cell types efficiently exclude oligonucleotides in vitro and require specific delivery systems, such as cationic lipids, to enhance uptake and subsequent antisense effects. Oligonucleotides are not readily transfected into leukaemia cell lines using cationic lipid sys...

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Bibliografiske detaljer
Main Authors: Giles, R V, Spiller, D G, Grzybowski, J, Clark, R E, Nicklin, P, Tidd, D M
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC147466/
https://ncbi.nlm.nih.gov/pubmed/9512525
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