High- to low-dose extrapolation: critical determinants involved in the dose response of carcinogenic substances.

Recent investigations on mechanism of carcinogenesis have demonstrated important quantitative relationships between the induction of neoplasia, the molecular dose of promutagenic DNA adducts and their efficiency for causing base-pair mismatch, and the extent of cell proliferation in target organ. Th...

Full description

Saved in:
Bibliographic Details
Main Authors: Swenberg, J A, Richardson, F C, Boucheron, J A, Deal, F H, Belinsky, S A, Charbonneau, M, Short, B G
Format: Artigo
Language:Inglês
Published: 1987
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474488/
https://ncbi.nlm.nih.gov/pubmed/3447904
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items