Detection of mutations in GC-rich DNA by bisulphite denaturing gradient gel electrophoresis.
Denaturing gradient gel electrophoresis (DGGE) in combination with PCR and 'GC-clamping' has proven highly efficient as a method for detection of DNA sequence differences. Due to strand dissociation phenomena, however, its use has been limited to the analysis of sequences with a relatively low conte...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9490806/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.6.1548 |
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