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The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano-electrical transducer channels

The most serious side-effect of the widely used aminoglycoside antibiotics is irreversible intracellular damage to the auditory and vestibular hair cells of the inner ear. The mechanism of entry into the hair cells has not been unequivocally resolved. Here we report that extracellular dihydrostrepto...

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Détails bibliographiques
Auteurs principaux: Marcotti, Walter, van Netten, Sietse M, Kros, Corné J
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474200/
https://ncbi.nlm.nih.gov/pubmed/15994187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.085951
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