P2X(2) knockout mice and P2X(2)/P2X(3) double knockout mice reveal a role for the P2X(2) receptor subunit in mediating multiple sensory effects of ATP

Extracellular ATP plays a role in nociceptive signalling and sensory regulation of visceral function through ionotropic receptors variably composed of P2X(2) and P2X(3) subunits. P2X(2) and P2X(3) subunits can form homomultimeric P2X(2), homomultimeric P2X(3), or heteromultimeric P2X(2/3) receptors....

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Detalhes bibliográficos
Main Authors: Cockayne, Debra A, Dunn, Philip M, Zhong, Yu, Rong, Weifang, Hamilton, Sara G, Knight, Gillian E, Ruan, Huai-Zhen, Ma, Bei, Yip, Ping, Nunn, Philip, McMahon, Stephen B, Burnstock, Geoffrey, Ford, Anthony PDW
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Integrative Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474198/
https://ncbi.nlm.nih.gov/pubmed/15961431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.088435
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