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P2X(2) knockout mice and P2X(2)/P2X(3) double knockout mice reveal a role for the P2X(2) receptor subunit in mediating multiple sensory effects of ATP

Extracellular ATP plays a role in nociceptive signalling and sensory regulation of visceral function through ionotropic receptors variably composed of P2X(2) and P2X(3) subunits. P2X(2) and P2X(3) subunits can form homomultimeric P2X(2), homomultimeric P2X(3), or heteromultimeric P2X(2/3) receptors....

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Bibliografiske detaljer
Main Authors: Cockayne, Debra A, Dunn, Philip M, Zhong, Yu, Rong, Weifang, Hamilton, Sara G, Knight, Gillian E, Ruan, Huai-Zhen, Ma, Bei, Yip, Ping, Nunn, Philip, McMahon, Stephen B, Burnstock, Geoffrey, Ford, Anthony PDW
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2005
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474198/
https://ncbi.nlm.nih.gov/pubmed/15961431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.088435
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