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Total-Genome Analysis of BRCA1/2-Related Invasive Carcinomas of the Breast Identifies Tumor Stroma as Potential Landscaper for Neoplastic Initiation

We have shown that the tumor microenvironment of sporadic breast cancer is diverse in genetic alterations and contributes to the cancer phenotype. The dynamic morphology of the mammary gland might be of special interest in hereditary breast/ovarian cancer syndrome (HBOC). We hypothesized that hotspo...

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Detalhes bibliográficos
Main Authors: Weber, Frank, Shen, Lei, Fukino, Koichi, Patocs, Attila, Mutter, George L., Caldes, Trinidad, Eng, Charis
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474086/
https://ncbi.nlm.nih.gov/pubmed/16685647
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