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Total-Genome Analysis of BRCA1/2-Related Invasive Carcinomas of the Breast Identifies Tumor Stroma as Potential Landscaper for Neoplastic Initiation

We have shown that the tumor microenvironment of sporadic breast cancer is diverse in genetic alterations and contributes to the cancer phenotype. The dynamic morphology of the mammary gland might be of special interest in hereditary breast/ovarian cancer syndrome (HBOC). We hypothesized that hotspo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weber, Frank, Shen, Lei, Fukino, Koichi, Patocs, Attila, Mutter, George L., Caldes, Trinidad, Eng, Charis
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Human Genetics 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474086/
https://ncbi.nlm.nih.gov/pubmed/16685647
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