Loss of mesenchymal bone morphogenetic protein signaling leads to development of reactive stroma and initiation of the gastric neoplastic cascade

Bmps are morphogens involved in various gastric cellular functions. Studies in genetically-modified mice have shown that Bmp disruption in gastric epithelial and stromal cell compartments leads to the development of tumorigenesis. Our studies have demonstrated that abrogation of gastric epithelial B...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Roy, Sébastien A. B., Allaire, Joannie M., Ouellet, Camille, Maloum-Rami, Faiza, Pomerleau, Véronique, Lemieux, Étienne, Babeu, Jean-Philippe, Rousseau, Jasmin, Paquet, Marilène, Garde-Granger, Perrine, Boudreau, François, Perreault, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016723/
https://ncbi.nlm.nih.gov/pubmed/27609464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32759
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