Aptamer mediated siRNA delivery

Nucleic acids that bind to cells and are subsequently internalized could prove to be novel delivery reagents. An anti-prostate specific membrane antigen aptamer that has previously been shown to bind to prostate tumor cells was coupled to siRNAs via a modular streptavidin bridge. The resulting conju...

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Библиографические подробности
Главные авторы: Chu, Ted C., Twu, Karen Y., Ellington, Andrew D., Levy, Matthew
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2006
Предметы:
Methods Online
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474074/
https://ncbi.nlm.nih.gov/pubmed/16740739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl388
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