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Aptamer mediated siRNA delivery

Nucleic acids that bind to cells and are subsequently internalized could prove to be novel delivery reagents. An anti-prostate specific membrane antigen aptamer that has previously been shown to bind to prostate tumor cells was coupled to siRNAs via a modular streptavidin bridge. The resulting conju...

詳細記述

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書誌詳細
主要な著者: Chu, Ted C., Twu, Karen Y., Ellington, Andrew D., Levy, Matthew
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474074/
https://ncbi.nlm.nih.gov/pubmed/16740739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl388
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