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Human Rad51 protein displays enhanced homologous pairing of DNA sequences resembling those at genetically unstable loci

DNA strand exchange, the central step of homologous recombination, is considered to occur approximately independently of DNA sequence content. However, certain prokaryotic and eukaryotic genomic loci display either an enhanced or reduced frequency of genetic exchange. Here we show that the Homo sapi...

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Autors principals: Seitz, Erica M., Kowalczykowski, Stephen C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474073/
https://ncbi.nlm.nih.gov/pubmed/16723430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl355
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