Co-expression of sCD40LIg and CTLA4Ig mediated by adenovirus prolonged mouse skin allograft survival

Objective: To investigate the role of simultaneous blockade of CD40/CD40L and B7/CD28 pathways in the immune tolerance via co-expression of sCD40LIg and CTLA4Ig mediated by replication-defective adenovirus. Methods: Ad-sCD40LIg-IRES(2)-CTLA4Ig, replication-defective adenovirus co-expressing sCD40LIg...

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Bibliographische Detailangaben
Hauptverfasser: Li, Zhao-lun, Tian, Pu-xun, Xue, Wu-jun, Wu, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Zhejiang University Press 2006
Schlagworte:
Biomedicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473999/
https://ncbi.nlm.nih.gov/pubmed/16691637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.2006.B0436
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