PREVENTION OF CHRONIC REJECTION IN MOUSE AORTIC ALLOGRAFTS BY COMBINED TREATMENT WITH CTLA4-IG AND ANTI-CD40 LIGAND MONOCLONAL ANTIBODY,

BACKGROUND: In this study, using a murine model of aortic allotransplantation, the role of blockade of signaling through CD28/B7 and CD40/CD40 ligand co-stimulatory pathways in the evolvement of posttransplant vasculopathy was examined. METHODS: Aortic allografts were transplanted across C57BL/10J (...

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Hauptverfasser: Sun, Hong, Subbotin, Vladimir, Chen, Christopher, Aitouche, Abdelouahab, Valdivia, Luis A., Sayegh, Mohammed H., Linsley, Peter S., Fung, John J., Starzl, Thomas E., Rao, Abdul S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975542/
https://ncbi.nlm.nih.gov/pubmed/9422428
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