Efficient 3'-end formation of human beta-globin mRNA in vivo requires sequences within the last intron but occurs independently of the splicing reaction.

Lignende værker

• Short donor site sequences inserted within the intron of beta-globin pre-mRNA serve for splicing in vitro.
  af: Mayeda, A, et al.
  Udgivet: (1988)
• Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expression.
  af: Collis, P, et al.
  Udgivet: (1990)
• The interaction between the first and last intron nucleotides in the second step of pre-mRNA splicing is independent of other conserved intron nucleotides.
  af: Ruis, B L, et al.
  Udgivet: (1994)
• Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm.
  af: Zhang, J, et al.
  Udgivet: (1998)
• DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression.
  af: Fraser, P, et al.
  Udgivet: (1990)