Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA.

Photoactivated methylene blue was used to damage purified DNA and the mitochondrial DNA (mtDNA) of human fibroblasts in culture. The primary product of this reaction is the DNA lesion 7-hydro-8-oxo-deoxyguanosine (8-oxo-dG). The DNA damage was quantitated using Escherichia coli formamidopyrimidine D...

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izdano v:	Nucleic Acids Res
Principais autores:	Anson, R M, Croteau, D L, Stierum, R H, Filburn, C, Parsell, R, Bohr, V A
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 1998
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9421531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.2.662
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