Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA.

Photoactivated methylene blue was used to damage purified DNA and the mitochondrial DNA (mtDNA) of human fibroblasts in culture. The primary product of this reaction is the DNA lesion 7-hydro-8-oxo-deoxyguanosine (8-oxo-dG). The DNA damage was quantitated using Escherichia coli formamidopyrimidine D...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Anson, R M, Croteau, D L, Stierum, R H, Filburn, C, Parsell, R, Bohr, V A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9421531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.2.662
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