Lipid Sulfates and Sulfonates Are Allosteric Competitive Inhibitors of the N-Terminal Phosphatase Activity of the Mammalian Soluble Epoxide Hydrolase

The EPXH2 gene encodes for the soluble epoxide hydrolase (sEH), a homodimeric enzyme with each monomer containing two domains with distinct activities. The C-terminal domain, containing the epoxide hydrolase activity (Cterm-EH), is involved in the metabolism of arachidonic acid epoxides, endogenous...

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Detaylı Bibliyografya
Asıl Yazarlar: Tran, Katherine L., Aronov, Pavel A., Tanaka, Hiromasa, Newman, John W., Hammock, Bruce D., Morisseau, Christophe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473036/
https://ncbi.nlm.nih.gov/pubmed/16142916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi050842g
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