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N-Substituted amino acid inhibitors of the phosphatase domain of the soluble epoxide hydrolase

The soluble epoxide hydrolase (sEH) is a bifunctional enzyme implicated in the regulation of inflammation. The N-terminal domain harbors a phosphatase activity (N-phos) with an affinity to lipid phosphomonoesters, and the C-terminal domain has an activity to hydrolyze anti-inflammatory lipid epoxide...

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書目詳細資料
發表在:Biochem Biophys Res Commun
Main Authors: Matsumoto, Naoki, Kataoka, Masaki, Hirosaki, Hibiki, Morisseau, Christophe, Hammock, Bruce D., Suzuki, Eriko, Hasumi, Keiji
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395850/
https://ncbi.nlm.nih.gov/pubmed/31146915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.05.088
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