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N-Substituted amino acid inhibitors of the phosphatase domain of the soluble epoxide hydrolase
The soluble epoxide hydrolase (sEH) is a bifunctional enzyme implicated in the regulation of inflammation. The N-terminal domain harbors a phosphatase activity (N-phos) with an affinity to lipid phosphomonoesters, and the C-terminal domain has an activity to hydrolyze anti-inflammatory lipid epoxide...
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| Publicado en: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7395850/ https://ncbi.nlm.nih.gov/pubmed/31146915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.05.088 |
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