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Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1

The tumor suppressor gene wild-type p53 encodes a labile protein that accumulates in cells after different stress signals and can cause either growth arrest or apoptosis. One of the p53 target genes, p53-inducible gene 3 (PIG3), encodes a protein with significant homology to oxidoreductases, enzymes...

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Main Authors: Asher, Gad, Lotem, Joseph, Cohen, Batya, Sachs, Leo, Shaul, Yosef
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC14730/
https://ncbi.nlm.nih.gov/pubmed/11158615
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