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SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
The mammalian cytoplasmic protein SirT2 is a member of the Sir2 family of NAD(+)-dependent protein deacetylases involved in caloric restriction-dependent life span extension. We found that SirT2 and its yeast counterpart Hst2 have a strong preference for histone H4K16Ac in their deacetylation activi...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Cold Spring Harbor Laboratory Press
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472900/ https://ncbi.nlm.nih.gov/pubmed/16648462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1412706 |
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