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Substitution of C-terminus of VEGFR-2 with VEGFR-1 promotes VEGFR-1 activation and endothelial cell proliferation

VEGFR-1 is devoid of ligand-dependent tyrosine autophosphorylation and its activation is not associated with proliferation of endothelial cells. The molecular mechanism responsible for this characteristic of VEGFR-1 is not known. In this study, we show that VEGFR-1 is devoid of ligand-dependent down...

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Bibliografiske detaljer
Main Authors: Meyer, Rosana D, Singh, Amrik, Majnoun, Fredric, Latz, Catharina, Lashkari, Kameran, Rahimi, Nader
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472702/
https://ncbi.nlm.nih.gov/pubmed/15107818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207712
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