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Regulation of progesterone receptor signaling by BRCA1 in mammary cancer
Inherited mutations of the BRCA1 gene (chromosome 17q21), a tumor suppressor, lead to an increased risk of breast cancer, ovarian cancer, and several other hormone-responsive tumor types. Over the last ten years, BRCA1 has been found to play major roles in DNA damage signaling, repair, and cell cycl...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Nuclear Receptor Signaling Atlas
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472667/ https://ncbi.nlm.nih.gov/pubmed/16741564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1621/nrs.04006 |
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