BRCA1 Regulates Acetylation and Ubiquitination of Estrogen Receptor-α

Inherited mutations of the breast cancer susceptibility gene BRCA1 confer a high risk for breast cancer development. The (300)RXKK and (266)KXK motifs have been identified previously as sites for acetylation of the estrogen receptor-α (ER-α), and (302)K was also found to be a site for BRCA1-mediated...

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Huvudupphovsmän: Ma, Yongxian, Fan, Saijun, Hu, Changyan, Meng, Qinghui, Fuqua, Suzanne A., Pestell, Richard G., Tomita, York A., Rosen, Eliot M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Endocrine Society 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802901/
https://ncbi.nlm.nih.gov/pubmed/19887647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0218
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