Regulation of progesterone receptor signaling by BRCA1 in mammary cancer

Inherited mutations of the BRCA1 gene (chromosome 17q21), a tumor suppressor, lead to an increased risk of breast cancer, ovarian cancer, and several other hormone-responsive tumor types. Over the last ten years, BRCA1 has been found to play major roles in DNA damage signaling, repair, and cell cycl...

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Dades bibliogràfiques
Autors principals: Katiyar, Pragati, Ma, Yongxian, Fan, Saijun, Pestell, Richard G., Furth, Priscilla A., Rosen, Eliot M.
Format: Artigo
Idioma:Inglês
Publicat: The Nuclear Receptor Signaling Atlas 2006
Matèries:
Perspective
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472667/
https://ncbi.nlm.nih.gov/pubmed/16741564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1621/nrs.04006
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