Vaccine-Induced Cellular Immune Responses Reduce Plasma Viral Concentrations after Repeated Low-Dose Challenge with Pathogenic Simian Immunodeficiency Virus SIVmac239

The goal of an AIDS vaccine regimen designed to induce cellular immune responses should be to reduce the viral set point and preserve memory CD4 lymphocytes. Here we investigated whether vaccine-induced cellular immunity in the absence of any Env-specific antibodies can control viral replication fol...

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Main Authors: Wilson, Nancy A., Reed, Jason, Napoe, Gnankang S., Piaskowski, Shari, Szymanski, Andy, Furlott, Jessica, Gonzalez, Edna J., Yant, Levi J., Maness, Nicholas J., May, Gemma E., Soma, Taeko, Reynolds, Matthew R., Rakasz, Eva, Rudersdorf, Richard, McDermott, Adrian B., O'Connor, David H., Friedrich, Thomas C., Allison, David B., Patki, Amit, Picker, Louis J., Burton, Dennis R., Lin, Jing, Huang, Lingyi, Patel, Deepa, Heindecker, Gwendolyn, Fan, Jiang, Citron, Michael, Horton, Melanie, Wang, Fubao, Liang, Xiaoping, Shiver, John W., Casimiro, Danilo R., Watkins, David I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472612/
https://ncbi.nlm.nih.gov/pubmed/16731926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00171-06
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