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The NS2 Protein of Human Respiratory Syncytial Virus Suppresses the Cytotoxic T-Cell Response as a Consequence of Suppressing the Type I Interferon Response

The NS1 and NS2 proteins of human respiratory syncytial virus (HRSV) have been shown to antagonize the type I interferon (IFN) response, an effect subject to host range constraints. We have now found that the HRSV NS2 protein strongly controls IFN induction in mouse cells in vitro, validating the us...

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Hlavní autoři: Kotelkin, Alexander, Belyakov, Igor M., Yang, Lijuan, Berzofsky, Jay A., Collins, Peter L., Bukreyev, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472589/
https://ncbi.nlm.nih.gov/pubmed/16731934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00181-06
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