Expression of Interleukin-4 by Recombinant Respiratory Syncytial Virus Is Associated with Accelerated Inflammation and a Nonfunctional Cytotoxic T-Lymphocyte Response following Primary Infection but Not following Challenge with Wild-Type Virus

The outcome of a viral infection or of immunization with a vaccine can be influenced by the local cytokine environment. In studies of experimental vaccines against respiratory syncytial virus (RSV), an increased stimulation of Th2 (T helper 2) lymphocytes was associated with increased immunopatholog...

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Detalhes bibliográficos
Main Authors: Bukreyev, Alexander, Belyakov, Igor M., Prince, Gregory A., Yim, Kevin C., Harris, Katie K., Berzofsky, Jay A., Collins, Peter L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181599/
https://ncbi.nlm.nih.gov/pubmed/16014914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.9515-9526.2005
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