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The NS2 Protein of Human Respiratory Syncytial Virus Suppresses the Cytotoxic T-Cell Response as a Consequence of Suppressing the Type I Interferon Response

The NS1 and NS2 proteins of human respiratory syncytial virus (HRSV) have been shown to antagonize the type I interferon (IFN) response, an effect subject to host range constraints. We have now found that the HRSV NS2 protein strongly controls IFN induction in mouse cells in vitro, validating the us...

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Detalhes bibliográficos
Main Authors: Kotelkin, Alexander, Belyakov, Igor M., Yang, Lijuan, Berzofsky, Jay A., Collins, Peter L., Bukreyev, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472589/
https://ncbi.nlm.nih.gov/pubmed/16731934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00181-06
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