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Antigenic and Immunogenic Characterization of Recombinant Baculovirus-Expressed Severe Acute Respiratory Syndrome Coronavirus Spike Protein: Implication for Vaccine Design

The spike (S) glycoprotein of severe acute respiratory syndrome coronavirus (SARS-CoV) mediates the receptor interaction and immune recognition and is considered a major target for vaccine design. However, its antigenic and immunogenic properties remain to be elucidated. In this study, we immunized...

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Detalhes bibliográficos
Main Authors: He, Yuxian, Li, Jingjing, Heck, Susanne, Lustigman, Sara, Jiang, Shibo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472569/
https://ncbi.nlm.nih.gov/pubmed/16731915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00083-06
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