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Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility
The human TGFB1 gene is polymorphic, and genetic variants are associated with altered cancer risk. However, human genetic association studies have had variable outcomes because TGFβ1 action is context-dependent. We used the murine skin model of chemical carcinogenesis in genetic linkage analysis of...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472440/ https://ncbi.nlm.nih.gov/pubmed/16702541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602581103 |
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